Roovers, Rob C. : rechercher sur Z-Library

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Don't use scam websites

Livres
Articles (33)
Les plus populaires
Liste
- Liste
- Tableau

1

Efficient inhibition of EGFR signalling and of tumour growth by antagonistic anti-EGFR Nanobodies

Rob C. Roovers, Toon Laeremans, Lieven Huang, Severine De Taeye, Arie J. Verkleij, Hilde Revets, Hans J. de Haard, Paul M. P. van Bergen en Henegouwen

Journal:

Cancer Immunology, Immunotherapy

Année:

2007

Langue:

english

Fichier:

PDF, 542 KB

english, 2007

2

Targeting hepatocyte growth factor receptor (Met) positive tumor cells using internalizing nanobody-decorated albumin nanoparticles

Heukers, Raimond, Altintas, Isil, Raghoenath, Smiriti, De Zan, Erica, Pepermans, Richard, Roovers, Rob C., Haselberg, Rob, Hennink, Wim E., Schiffelers, Raymond M., Kok, Robbert J., van Bergen en Hene

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 2.83 MB

english, 2014

3

A bispecific antibody antagonizes pro-survival CD40 signaling and promotes VÎ³9VÎ´2 T cell-mediated antitumor responses in human B-cell malignancies

de Weerdt, Iris, Lameris, Roeland, Scheffer, George L, Vree, Jana, de Boer, Renate, Stam, Anita G, van de Ven, Rieneke, Levin, Mark-David, Pals, Steven T., Roovers, Rob C, Parren, Paul W.H.I., de Grui

Journal:

Cancer Immunology Research

Année:

2020

Fichier:

PDF, 2.68 MB

2020

4

Construction and characterization of a bispecific diabody for retargeting T cells to human carcinomas

Wijnand Helfrich, Bart Jan Kroesen, Rob C. Roovers, Lidia Westers, Grietje Molema, Hennie R. Hoogenboom, Lou de Leij

Journal:

International Journal of Cancer

Année:

1998

Langue:

english

Fichier:

PDF, 161 KB

english, 1998

5

Evidence for a bias toward intracellular antigens in the local humoral anti-tumor immune response of a colorectal cancer patient revealed by phage display

Rob C. Roovers, Edith van der Linden, Han Zijlema, Adriaan de Bruïne, Jan-Willem Arends, Hennie R. Hoogenboom

Journal:

International Journal of Cancer

Année:

2001

Langue:

english

Fichier:

PDF, 948 KB

english, 2001

6

A biparatopic anti-EGFR nanobody efficiently inhibits solid tumour growth

Rob C. Roovers, Maria J.W.D. Vosjan, Toon Laeremans, Rachid el Khoulati, Renée C.G. de Bruin, Kathryn M. Ferguson, Arie J. Verkleij, Guus A.M.S. van Dongen, Paul M.P. van Bergen en Henegouwen

Journal:

International Journal of Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2011

7

Measuring health-related quality of life in women with urogenital dysfunction: The urogenital distress inventory and incontinence impact questionnaire revisited

C. Huub van der Vaart, J. Rob J. de Leeuw, Jan-Paul W.R. Roovers, A. Peter M. Heintz

Journal:

Neurourology and Urodynamics

Année:

2003

Langue:

english

Fichier:

PDF, 138 KB

english, 2003

8

Facile labelling of an anti-epidermal growth factor receptor Nanobody with68Ga via a novel bifunctional desferal chelate for immuno-PET

Maria J. W. D. Vosjan, Lars R. Perk, Rob C. Roovers, Gerard W. M. Visser, Marijke Stigter-van Walsum, Paul M. P. van Bergen en Henegouwen, Guus A. M. S. van Dongen

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Année:

2011

Langue:

english

Fichier:

PDF, 388 KB

english, 2011

9

In vitro characterisation of a monovalent and bivalent form of a fully human anti Ep-CAM phage antibody

Rob C. Roovers, Edith van der Linden, Adriaan P. de Bruïne, Jan-Willem Arends, Hennie R. Hoogenboom

Journal:

Cancer Immunology, Immunotherapy

Année:

2001

Langue:

english

Fichier:

PDF, 256 KB

english, 2001

10

Downregulation of EGFR by a novel multivalent nanobody-liposome platform

Sabrina Oliveira, Raymond M. Schiffelers, Joris van der Veeken, Roy van der Meel, Ranitha Vongpromek, Paul M.P. van Bergen en Henegouwen, Gert Storm, Rob C. Roovers

Journal:

Journal of Controlled Release

Année:

2010

Langue:

english

Fichier:

PDF, 1012 KB

english, 2010

11

Tumor-targeted Nanobullets: Anti-EGFR nanobody-liposomes loaded with anti-IGF-1R kinase inhibitor for cancer treatment

Roy van der Meel, Sabrina Oliveira, Isil Altintas, Rob Haselberg, Joris van der Veeken, Rob C. Roovers, Paul M.P. van Bergen en Henegouwen, Gert Storm, Wim E. Hennink, Raymond M. Schiffelers, Robbert

Journal:

Journal of Controlled Release

Année:

2012

Langue:

english

Fichier:

PDF, 820 KB

english, 2012

12

Selection and characterization of KDEL-specific VHH antibody fragments and their application in the study of ER resident protein expression

Rinse Klooster, Michael R. Eman, Quint le Duc, Peter Verheesen, C. Theo Verrips, Rob C. Roovers, Jan A. Post

Journal:

Journal of Immunological Methods

Année:

2009

Langue:

english

Fichier:

PDF, 1.00 MB

english, 2009

13

Design and application of diabodies, triabodies and tetrabodies for cancer targeting

Aneta Todorovska, Rob C. Roovers, Olan Dolezal, Alexander A. Kortt, Hennie R. Hoogenboom, Peter J. Hudson

Journal:

Journal of Immunological Methods

Année:

2001

Langue:

english

Fichier:

PDF, 1.96 MB

english, 2001

14

Model systems to study the parameters determining the success of phage antibody selections on complex antigens

Ricardo Mutuberria, Hennie R Hoogenboom, Edith van der Linden, Adriaan P de Bruı̈ne, Rob C Roovers

Journal:

Journal of Immunological Methods

Année:

1999

Langue:

english

Fichier:

PDF, 161 KB

english, 1999

15

Guided selection of a pan carcinoma specific antibody reveals similar binding characteristics yet structural divergence between the original murine antibody and its human equivalent

Sigrid H.W Beiboer, Anneke Reurs, Rob C Roovers, Jan-Willem Arends, Nick R Whitelegg, Anthony R Rees, Hennie R Hoogenboom

Journal:

Journal of Molecular Biology

Année:

2000

Langue:

english

Fichier:

PDF, 713 KB

english, 2000

16

Association Between Urogenital Symptoms and Depression in Community-Dwelling Women Aged 20 to 70 Years

Carl Huibert van der Vaart, Jan-Paul W.R. Roovers, J. Rob J. de Leeuw, A. Peter M. Heintz

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 84 KB

english, 2007

17

Regulation of Tiam1–Rac signalling

Alexander E. Mertens, Rob C. Roovers, John G. Collard

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 205 KB

english, 2003

18

Antibody phage display technology and its applications

Hennie R Hoogenboom, Adriaan P de Bruı̈ne, Simon E Hufton, René M Hoet, Jan-Willem Arends, Rob C Roovers

Journal:

Immunotechnology

Année:

1998

Langue:

english

Fichier:

PDF, 555 KB

english, 1998

19

Amphiregulin Enhances Regulatory T Cell-Suppressive Function via the Epidermal Growth Factor Receptor

Zaiss, Dietmar M.W., van Loosdregt, Jorg, Gorlani, Andrea, Bekker, Cornelis P.J., Gröne, Andrea, Sibilia, Maria, van Bergen en Henegouwen, Paul M.P., Roovers, Rob C., Coffer, Paul J., Sijts, Alice J.A

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 875 KB

english, 2013

20

Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains

Schmitz, Karl R., Bagchi, Atrish, Roovers, Rob C., van Bergen en Henegouwen, Paul M.P., Ferguson, Kathryn M.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 2.07 MB

english, 2013

21

Single Quantum Dot Tracking Coupled to a Three-State HMM Provides New Mechanistic Insight Into erbB1 Homodimerization

Low-Nam, Shalini T., Lidke, Keith A., Cutler, Patrick J., Roovers, Rob C., van Bergen, Paul M.P., Henegouwen, en, Wilson, Bridget S., Lidke, Diane S.

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 35 KB

english, 2011

22

Determination of Single Molecule erbB1 Homodimer Lifetimes Using Single Quantum Dot Tracking and a Diffusive Hidden Markov Model

Low-Nam, Shalini T., Lidke, Keith A., Cutler, Patrick J., Roovers, Rob C., van Bergen en Henegouwen, Paul M.P., Wilson, Bridget S., Lidke, Diane S.

Journal:

Biophysical Journal

Année:

2010

Langue:

english

Fichier:

PDF, 123 KB

english, 2010

23

Meeting announcements

Low-Nam, Shalini, Lidke, Keith, Roovers, Rob, van Bergen en Henegouwen, Paul, Wilson, Bridget, Lidke, Diane

Journal:

Reproductive Toxicology

Année:

1987

Langue:

english

Fichier:

PDF, 93 KB

english, 1987

24

Multi-color Single Quantum Dot Tracking To Characterize Membrane Receptor Interactions On Living Cells

Low-Nam, Shalini, Lidke, Keith, Roovers, Rob, van Bergen en Henegouwen, Paul, Wilson, Bridget, Lidke, Diane

Journal:

Biophysical Journal

Année:

2009

Langue:

english

Fichier:

PDF, 40 KB

english, 2009

25

Correction

Low-Nam, Shalini, Lidke, Keith, Roovers, Rob, van Bergen en Henegouwen, Paul, Wilson, Bridget, Lidke, Diane

Journal:

Journal of the American Academy of Dermatology

Année:

1989

Langue:

english

Fichier:

PDF, 51 KB

english, 1989

26

Inverse Agonism of Histamine H2Antagonists Accounts for Upregulation of Spontaneously Active Histamine H2Receptors

Martine J. Smit, Rob Leurs, Astrid E. Alewijnse, Joeri Blauw, Gerard P. Van Nieuw Amerongen, Yvonne Van De Vrede, Edwin Roovers and Henk Timmerman

Journal:

Proceedings of the National Academy of Sciences

Année:

1996

Langue:

english

Fichier:

PDF, 1.20 MB

english, 1996

27

ErbB1 dimerization is promoted by domain co-confinement and stabilized by ligand binding

Low-Nam, Shalini T, Lidke, Keith A, Cutler, Patrick J, Roovers, Rob C, van Bergen en Henegouwen, Paul M P, Wilson, Bridget S, Lidke, Diane S

Journal:

Nature Structural and Molecular Biology

Année:

2011

Langue:

english

Fichier:

PDF, 836 KB

english, 2011

28

Highly specific and potently activating Vγ9Vδ2-T cell specific nanobodies for diagnostic and therapeutic applications

de Bruin, Renée C.G., Lougheed, Sinéad M., van der Kruk, Liza, Stam, Anita G., Hooijberg, Erik, Roovers, Rob C., van Bergen en Henegouwen, Paul M.P., Verheul, Henk M.W., de Gruijl, Tanja D., van der V

Journal:

Clinical Immunology

Année:

2016

Langue:

english

Fichier:

PDF, 940 KB

english, 2016

29

High affinity nanobodies against human epidermal growth factor receptor selected on cells by E. coli display

Salema, Valencio, Mañas, Carmen, Cerdán, Lidia, Piñero-Lambea, Carlos, Marín, Elvira, Roovers, Rob C., van Bergen en Henegouwen, Paul M.P., Fernández, Luis Ángel

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.75 MB

english, 2016

30

Autophagy inhibition as a potential future targeted therapy for ETV6-RUNX1 driven B-cell precursor acute lymphoblastic leukemia

Polak, Roel, Bierings, Marc B., van der Leije, Cindy S., Sanders, Mathijs A., Roovers, Onno, Marchante, Joao R.M., Boer, Judith M., Cornelissen, Jan J., Pieters, Rob, den Boer, Monique L., Buitenhuis,

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 4.23 MB

english, 2018

31

The architecture of EGFR’s basal complexes reveals autoinhibition mechanisms in dimers and oligomers

Zanetti-Domingues, Laura C., Korovesis, Dimitrios, Needham, Sarah R., Tynan, Christopher J., Sagawa, Shiori, Roberts, Selene K., Kuzmanic, Antonija, Ortiz-Zapater, Elena, Jain, Purvi, Roovers, Rob C.,

Journal:

Nature Communications

Année:

2018

Langue:

english

Fichier:

PDF, 2.68 MB

english, 2018

32

MCLA-117, a CLEC12AxCD3 bispecific antibody targeting a leukaemic stem cell antigen, induces T cell-mediated AML blast lysis

van Loo, Pieter Fokko, Hangalapura, Basav N., Thordardottir, Soley, Gibbins, John D., Veninga, Henrike, Hendriks, Linda J. A., Kramer, Arjen, Roovers, Rob C., Leenders, Marij, de Kruif, John, Doornbos

Journal:

Expert Opinion on Biological Therapy

Année:

2019

Langue:

english

Fichier:

PDF, 2.05 MB

english, 2019

33

MCLA-117, a CLEC12AxCD3 bispecific antibody targeting a leukaemic stem cell antigen, induces T cell-mediated AML blast lysis

van Loo, Pieter Fokko, Hangalapura, Basav N., Thordardottir, Soley, Gibbins, John D., Veninga, Henrike, Hendriks, Linda J. A., Kramer, Arjen, Roovers, Rob C., Leenders, Marij, de Kruif, John, Doornbos

Journal:

Expert Opinion on Biological Therapy

Année:

2019

Fichier:

PDF, 2.05 MB

2019